Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 117405 | 117405 | Spain | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 87 |
| 2 | AZT+ DDC | 144 |
| 3 | AZT+ DDC+ SQV | 94 |
| 4 | DDI+ D4T+ RTV+ SQV | 65 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, L90M | V11I, F53L | I13V, I15V, K20R, E35D, M36I, N37E, I62V, L63P, A71V, V77I, Q92K |
| >117405| codons 1-99 PQITLWQRPLITVKVGGQLREALLDTGADDTVLEDIELPGRWKPKMIGGIGGLVKVRQYD QVPIEICGHKVIGTVLIGPTPVNIIGRNLMTKIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, T215F | K20R, I135L, Q174R, R211E, V245I |
| >117405| codons 1-249 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKRNPDIVI YQYMDDLYVGSDLEIGQHRTKIEELRQHLLEWGFFTPDKKHQKEPPFLWMGYELHPDKWT VQPIILPEK |
References
| Author | Title | Citation |
| Tural, C | Clinical utility of HIV-1 genotyping and expert advice: the Havana trial. | AIDS, 2002 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |