Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 110855 | 110855 | Spain | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 105 |
| 2 | AZT+ DDI | 87 |
| 3 | AZT+ DDI+ 3TC | 69 |
| 4 | AZT+ DDI+ 3TC+ RTV | 19 |
| 5 | D4T+ 3TC+ RTV | 47 |
| 6 | D4T+ 3TC+ RTV+ SQV | 55 |
| 7 | ABC+ EFV+ RTV+ SQV+ NFV | 1 |
| 8 | 3TC+ EFV+ RTV+ SQV+ NFV | 41 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, K70R, M184V | T215V, K219Q | K103N | V108I | K20R, V60I, V90I, I135T, S162Y, I195T, G196K, Q197L, Q207E, L228H |
| >110855| codons 1-250 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTELEKEGKISKIGPENPYNTPI FAIKKKNSDRWRKLVDFRELNKRTQDFWEIQLGIPHPAGLKKNKSVTILDVGDAYFSVPL DKDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQYSMTKILEPFRKQNPDIVI YQYVDDLYVGSDLETKLHRTKIEELREHLLRWGFVTPDQKHQKEPPFHWMGYELHPDKWT VQPIVLPEKD |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82A, I84V, L90M | L33F, K43T, F53L | I13V, E35D, M36L, N37T, R57K, D60E, L63P, A71V, V77I |
| >110855| codons 1-99 PQITLWQRPLVTVKIGGQLKEALLDTGADDTVFEDLTLPGRWTPKMIGGIGGLVKVKQYE QIPIEICGHKVIGTVLIGPTPANVIGRNLMTQIGCTLNF |
References
| Author | Title | Citation |
| Tural, C | Clinical utility of HIV-1 genotyping and expert advice: the Havana trial. | AIDS, 2002 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |