Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 57699 | 57699 | Spain | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | DDI+ D4T+ NVP | 25 |
| 2 | None | 4 |
| 3 | AZT+ 3TC+ IDV | 3 |
| 4 | 3TC+ NVP+ IDV | 27 |
| 5 | 3TC+ NVP+ NFV | 29 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | K101E, G190A | R83K, E169D, D177E, I178V, T200E, E204K, R211K, F214L, V245E, E248D |
| >57699| codons 1-250 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKKTQDFWEVQLGIPHPAGLEKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILDPFRKQNPEVVI YQYVDDLYVASDLEIGQHREKIEKLRQHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIELPDKD |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N | N88D | I62V, L63S, A71V, V77I, I93L |
| >57699| codons 1-99 PQITLWQRPLVTIKIGGQLKEALLDTGADNTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD QVSIEICGHKVIGTVLIGPTPVNIIGRDLLTQLGCTLNF |
References
| Author | Title | Citation |
| Tural, C | Clinical utility of HIV-1 genotyping and expert advice: the Havana trial. | AIDS, 2002 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |