Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 50331 | 50331 | Spain | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ DDC | 79 |
| 2 | AZT+ DDC+ 3TC | 7 |
| 3 | D4T+ 3TC+ IDV | 95 |
| 4 | DDI+ D4T+ NVP | 60 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10V, T12I, I15V, G16E, P39T, I64V |
| >50331| codons 1-99 PQITLWQRPVVIIKVEGQLKEALLDTGADDTVLEEMNLTGRWKPKMIGGIGGFIKVRQYD QILVEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K65R, K70R, Q151M | V75I, F77L, F116Y | V106M, G190A | F227L | E42K, S68N, V118I, K122E, R125G, I135T, K166R, K173E, F214L | F124S |
| >50331| codons 1-250 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMKKEGKISKIGPENPYNTPV FAIKRKDNTRWRKLIDLRELNKRTQDFWEVQLGIPHPAGLKKKKSMTVLDVGDAYYSIPL DEDSGKYTAFTIPSTNNETPGIRYQYNVLPMGWKGSPAIFQSSMTRILEPFREQNPDIVI YQYMDDLYVASDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPLLWMGYELHPDKWT VQPIVLPEKD |
References
| Author | Title | Citation |
| Tural, C | Clinical utility of HIV-1 genotyping and expert advice: the Havana trial. | AIDS, 2002 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |