Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 20619 | 20619 | Spain | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 3 |
| 2 | AZT+ DDC | 35 |
| 3 | AZT+ 3TC | 87 |
| 4 | D4T+ 3TC+ IDV | 21 |
| 5 | DDI+ D4T+ RTV+ SQV | 39 |
| 6 | NVP+ RTV+ NFV | 32 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, V82T, I84V | L24I, K43T, T74P | L10I, E35D, M36I, N37D, L63P, A71V, I93L |
| >20619| codons 1-99 PQITLWQRPIVTIKIGGQLKEALIDTGADDTVLEDIDLPGRWTPKIIGGIGGFVKVRQYD QIPIEICGHKVIGPVLVGPTPTNVIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L210W | T215D | Y188L | K22R, K49R, V90I, A98S, V118I, Q197P, E203K, R211K, K223E | G15R, R143K |
| >20619| codons 1-250 PISPIETVPVKLKPRMDGPKVRQWPLTEEKIKALVEICTELEKEGKISRIGPENPYNTPV FAIKKKNSTKWRKLVDFRELNKRTQDFWEIQLGIPHPSGLKKKKSVTVLDVGDAYFSIPL DKDFRKYTAFTIPSINNETPGIKYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYMDDLLVGSDLEIGPHRTKIKELRQHLWKWGFDTPDKKHQEEPPFLWMGYELHPDKWT VQPIVLPEKD |
References
| Author | Title | Citation |
| Tural, C | Clinical utility of HIV-1 genotyping and expert advice: the Havana trial. | AIDS, 2002 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |