Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 9460 | 9460 | Spain | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 142 |
| 2 | AZT+ 3TC | 116 |
| 3 | D4T+ 3TC+ SQV | 8 |
| 4 | DDI+ D4T+ RTV | 103 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R | T215V, K219Q | K20R, K43E, K49R, V60I, T69N, D123E, S162N, D177E, R211K, F214L, D218E |
| >9460| codons 1-240 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTEMEEEGKISRIGPENPYNTPI FAIKKKNSNRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQNSMTKILEPFRKQNPEIVI YQYMDDLYVGSDLEIGQHRTKIEELRQHLLKWGLVTPEQKHQKEPPFLWMGYELHPDKWT |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82A, L90M | L10I, I15V, K20R, M36I, N37S, R57K, L63P, A71V |
| >9460| codons 1-99 PQITLWQRPIVTIKVGGQLREALLDTGADDTVLEEISLPGRWKPKMIGGIGGFVKVKQYD QIPIEICGHKVIGTVLVGPTPANIIGRNLMTQIGCTLNF |
References
| Author | Title | Citation |
| Tural, C | Clinical utility of HIV-1 genotyping and expert advice: the Havana trial. | AIDS, 2002 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |