Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| UK4480 | UK4480 | U.K. | 2002 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | EFV+ 3TC+ AZT | 38 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, M36L, N37E, R41K, L63LP, H69K, K70R, L89IM |
| >UK4480| codons 1-99 PQITLWQRPLVTVKIGGQLKEALLDTGADDTVLEELELPGKWKPKMIGGIGGFIKVRQYD QIPIEICGKRAIGTVLVGPTPVNIIGRNILTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | K103N | I31L, V35T, T39E, E40D, S48ST, K49R, K122E, I135T, K173A, Q174K, D177E, T200A, Q207E, R211K | Q222QH, L228CR |
| >UK4480| codons 1-230 PISPIETVPVKLKPGMDGPKVKQWPLTEEKLKALTEICEDMEKEGKITRIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPEIVI YQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGFTTPDKKHHKEPPFCWM |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |