<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
UK4480 UK4480 U.K. 2002 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 EFV+ 3TC+ AZT 38

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, M36L, N37E, R41K, L63LP, H69K, K70R, L89IM  
>UK4480| codons 1-99
PQITLWQRPLVTVKIGGQLKEALLDTGADDTVLEELELPGKWKPKMIGGIGGFIKVRQYD
QIPIEICGKRAIGTVLVGPTPVNIIGRNILTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V   K103N   I31L, V35T, T39E, E40D, S48ST, K49R, K122E, I135T, K173A, Q174K, D177E, T200A, Q207E, R211K Q222QH, L228CR
>UK4480| codons 1-230
PISPIETVPVKLKPGMDGPKVKQWPLTEEKLKALTEICEDMEKEGKITRIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL
DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPEIVI
YQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGFTTPDKKHHKEPPFCWM

References
Author Title Citation
Non-B Workgroup Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005