Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| UK4280 | UK4280 | U.K. | 2002 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NVP+ 3TC+ AZT | 205 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | K101E, G190A | A98G | K11T, K20R, V35T, K122E, D123S, I135T, E138A, K173S, Q174K, D177G, V179I, I202V, Q207D, R211S, F214L | E42K |
| >UK4280| codons 1-234 PISPIETVPVTLKPGMDGPRVKQWPLTEEKIKALTEICTEMKKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPGGLEKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSTNNATPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRSKNPGIII YQYVDDLYVASDLEIGQHRTKVEELRDHLLSWGLTTPDKKHQKEPPFLWMGYEL |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, L19LI, E35D, M36I, R41K, K45R, R57K, H69K, L89M |
| >UK4280| codons 1-99 PQITLWQRPLVTVKIGGQIKEALLDTGADDTVLEDINLPGKWKPRMIGGIGGFIKVKQYD QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |