Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| UK4799 | ASRU4799 | U.K. | 2003 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | EFV+ 3TC+ AZT | 17 |
| 2 | None | 8 |
| 3 | AZT+ NVP+ 3TC | 21 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | K101KE, G190A | V35T, T39E, S48T, K122E, D123S, I135IL, E138A, K173T, Q174K, T200A, I202V, Q207E, F214L | P225PL |
| >ASRU4799| codons 1-229 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLEKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSLNNATPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPDIVI YQYVDDLYVASDLEIGQHRAKVEELREHLLRWGLTTPDKKHQKELPFLW |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I3V, T12S, I15V, L19I, M36I, R41K, D60E, Q61D, H69K, V82I, L89I, I93L |
| >ASRU4799| codons 1-99 PQVTLWQRPLVSIKVGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYE DILIEICGKKAIGTVLVGPTPINIIGRNILTQLGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |