Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| UK5009 | UK5009 | U.K. | 2003 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | EFV+ 3TC+ AZT | 154 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | Y181C | E6K, K32E, V35T, E36A, T39A, S48T, E53D, K102R, K122E, I135T, T139I, S162H, K173T, D177E, Q207E, R211K, H221C |
| >UK5009| codons 1-234 PISPIKTVPVKLKPGMDGPKVKQWPLTEEKIEALTAICAEMEKEGKITKIGPDNPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKRKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSTNNEIPGIRYQYNVLPQGWKGSPAIFQHSMTKILEPFRTQNPEIVI CQYVDDLYVGSDLEIGQHRTKIEELREHLLKWGFTTPDKKCQKEPPFLWMGYEL |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19I, M36I, R41K, Q61H, L63P, C67W, H69K, I72V, L89M, I93L |
| >UK5009| codons 1-99 PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD HIPIEIWGKKAVGTVLVGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |