<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
UK5009 UK5009 U.K. 2003 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 EFV+ 3TC+ AZT 154

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V   Y181C   E6K, K32E, V35T, E36A, T39A, S48T, E53D, K102R, K122E, I135T, T139I, S162H, K173T, D177E, Q207E, R211K, H221C  
>UK5009| codons 1-234
PISPIKTVPVKLKPGMDGPKVKQWPLTEEKIEALTAICAEMEKEGKITKIGPDNPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKRKKSVTVLDVGDAYFSVPL
DEDFRKYTAFTIPSTNNEIPGIRYQYNVLPQGWKGSPAIFQHSMTKILEPFRTQNPEIVI
CQYVDDLYVGSDLEIGQHRTKIEELREHLLKWGFTTPDKKCQKEPPFLWMGYEL

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19I, M36I, R41K, Q61H, L63P, C67W, H69K, I72V, L89M, I93L  
>UK5009| codons 1-99
PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD
HIPIEIWGKKAVGTVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Non-B Workgroup Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005