Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| UK4758 | UK4758 | U.K. | 2003 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ D4T+ EFV | 69 |
| 2 | None | 26 |
| 3 | EFV+ 3TC+ AZT | 11 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | K103N | P225H | E6EK, K20KR, V21I, V35T, E36A, T39E, E40D, S48T, E53ED, W88C, V90VI, D121Y, K122E, S162Y, K173A, D177E, I195L, T200A, Q207D, R211K |
| >UK4758| codons 1-232 PISPIKTVPVKLKPGMDGPRIKQWPLTEEKIKALTAICEDMEKEGKITKIGPDNPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFCEIQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL YEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQYSMTKILEPFRAQNPEIVI YQYVDDLYVGSDLELGQHRAKIEELRDHLLKWGFTTPDKKHQKEHPFLWMGY |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12TS, I15V, L19I, M36I, N37S, R41K, H69K, L89M, I93L |
| >UK4758| codons 1-99 PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEEISLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |