<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
UK4684 UK4684 U.K. 2003 HIV1 D Plasma None

Treatment History
Order Regimen Weeks
1 EFV+ 3TC+ AZT 17

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10V, I13V, K20R, M36I, N37D, R41K, D60E, I64V  
>UK4684| codons 1-99
PQITLWQRPVVTVKIGGQLREALLDTGADDTVLEEIDLPGKWKPKMIGGIGGFIKVRQYE
QILVEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V   K103N   V35T, T39K, K43D, D121Y, K122E, D123E, I135T, S162A, D177E, I178M, T200M, Q207E, R211K  
>UK4684| codons 1-234
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICKEMEDEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL
YEEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRKQNPEMVI
YQYVDDLYVGSDLEIGQHRMKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYEL

References
Author Title Citation
Non-B Workgroup Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005