Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| F74928 | F74928 | U.K. | 2003 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+ NVP+ DDI | 26 |
| 2 | NVP+ AZT+ 3TC | 175 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | Y181C | E6K, V35T, T39L, D121H, K122E, I135T, T139R, I142V, K173A, Q174K, D177E, Q207A, R211S, D250E, T286A, E291D, V292I, I293V, P294T, E312D, S322A |
| >F74928| codons 1-334 PISPIKTVPVKLKPGMDGPKVKQWPLTEEKIKALTEICLEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL HEDFRKYTAFTIPSTNNERPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPEIVI CQYVDDLYVGSDLEIGQHRTKIEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKESWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDIVTLTEEAE LELAENREILKDPVHGVYYDPAKDLIAEIQKQGQ |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12A, I13V, E35D, M36I, N37D, R41K, R57K, D60E, H69K, L89M |
| >F74928| codons 1-99 PQITLWQRPLVAVKIGGQLKEALLDTGADDTVLEDIDLPGKWKPKMIGGIGGFIKVKQYE QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Weber, J | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |