Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| F69976 | F69976 | U.K. | 2003 | HIV1 | D | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NFV+ 3TC+ D4T | 39 |
| 2 | Unknown | 130 |
| 3 | LPV+ EFV+ ABC | 96 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K103N | V35T, V60I, K122E, I135T, I142T, E169D, R172K, D177E, I178L, Q197E, T200IM, E204K, Q207E, R211K, F214L, V245T, E248X, K249KR, D250DE, S251I, A272P, T286TA, I293V, I329V |
| >F69976| codons 1-335 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSTNNETPGTRYQYNVLPQGWKGSPAIFQSSMTKILDPFKKQNPELVI YQYMDDLYVGSDLEIGEHRMKIEKLREHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPITLPXREIWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTEVVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEVQKQGQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, E35ED, M36I, R41K, L63P, I64V, I72IV |
| >F69976| codons 1-99 PQITLWQRPLVSIKIGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QIPVEICGHKAVGTVLVGPTPVNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Weber, J | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |