Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| M36208 | M36208 | U.K. | 2003 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ 3TC+ NFV | 69 |
| 2 | Unknown | 17 |
| 3 | NVP+ DDI+ D4T | 146 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I15V, L19I, M36L, R41K, L63S, H69K, L89M, I93L |
| >M36208| codons 1-99 PQITLWQRPLVTIKVGGQIKEALLDTGADDTVLEELNLPGKWKPKMIGGIGGFIKVRQYD QISIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K65KR, D67N, K70R | K219Q | V106VM, Y181YC, G190A | A98G | E6EK, V8I, V35T, T39E, S48T, K122E, D123DN, K173A, D177E, T200A, E203K, Q207E, R211K, V245Q, S251SN, A272P, K277R, E291D, V292I, I293V |
| >M36208| codons 1-333 PISPIKTIPVKLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEGKITKIGPENPYNTPV FAIKRKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPGGLKKKKSMTVLDVGDAYFSVPL DENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAQNPEIVI CQYMDDLYVASDLEIGQHRAKIKELREHLLKWGFTTPDQKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDNWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQG |
References
| Author | Title | Citation |
| Weber, J | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |