Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| F40883 | F40883 | U.K. | 2003 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NVP+ ABC+ D4T+ DDI | 4 |
| 2 | ABC+ DDI+ D4T | 113 |
| 3 | NVP+ NFV+ AZT+ 3TC | 56 |
| 4 | Unknown | 30 |
| 5 | TDF+ LPV+ 3TC | 49 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, I15V, K20KR, E35D, M36I, R41K, R57K, H69K, L89M |
| >F40883| codons 1-99 PQITLWQRPLVTVKVGGQLREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| E6D, V35T, K49R, V60I, K122E, D123S, I135T, K173AS, Q174K, D177E, V179I, G196E, T200A, Q207A, R211S, V245E, D250E, K281R, T286A, E291D, V292I, I293V, E312D |
| >F40883| codons 1-334 PISPIDTVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISRIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRSKNPEIII YQYMDDLYVGSDLEIEQHRAKIEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIELPEKESWTVNDIQKLVGKLNWASQIYAGIKVKQLCRLLRGAKALTDIVPLTEEAE LELAENREILKDPVHGVYYDPSKDLIAEIQKQGQ |
References
| Author | Title | Citation |
| Weber, J | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |