Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| M86744 | M86744 | U.K. | 2003 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | RTV+ IDV+ 3TC+ AZT | 13 |
| 2 | EFV+ DDI+ AZT | 187 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12PS, I13V, I15V, L19T, K20R, M36I, N37D, R41K, D60E, Q61E, H69K, I72IR, T74A, L89M, I93L |
| >M86744| codons 1-99 PQITLWQRPLVSVKVGGQTREALLDTGADDTVLEEIDLPGKWKPKMIGGIGGFIKVRQYE EILIEICGKKARGAVLVGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70R, L74LV, L210W, T215Y | K103N, V106M | V35T, E36A, T39D, S48T, K122E, D123N, I135T, S162C, K173A, Q174K, D177E, T200A, Q207E, R211K, V245Q, A272P, K277R, E291D, V292I, I293V, D320DY, Q330QH |
| >M86744| codons 1-333 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICDELEKEGKITKIGPENPYNTPV FAIKKKNSTRWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSMTVLDVGDAYFSVPL DENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRAKNPEIVI YQYMDDLYVGSDLEIGQHRAKIEELREHLWKWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTDIVPLTEEAE LELAENREILKEPVHGVYYYPSKDLIAEIHKQG |
References
| Author | Title | Citation |
| Weber, J | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |