Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| M86254 | M86254 | U.K. | 2003 | HIV1 | CRF02_AG | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | LPV+ 3TC+ AZT | 8 |
| 2 | NFV+ AZT+ 3TC | 135 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| N88NS | L10LV, I13V, K14N, K20I, L33LV, M36I, N37ND, L63P, I66IF, H69K, K70KR, A71AT, T74TS, L89IM |
| >M86254| codons 1-99 PQITLWQRPVVTVNIGGQLIEALLDTGADDTVVEEIDLPGRWKPKMIGGIGGFIKVRQYD QIPIEFCGKRTIGSVLVGPTPVNIIGRSMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | K20KR, V35T, V60I, I135V, S162A, K173T, Q174K, D177E, I178M, T200A, Q207E, R211K, F214FL, P243T, V245Q, A272P, T286A, E291ED, V292I, I293V, S322T, I326V |
| >M86254| codons 1-334 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRTKNPEMVI YQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQTIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPTKDLVAEIQKQGQ |
References
| Author | Title | Citation |
| Weber, J | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |