<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
F36402 F36402 U.K. 2003 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+ AZT+ IDV 13
2 AZT+ 3TC 8
3 SQV+ AZT+ 3TC 52
4 Unknown 230

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I84V, L90M L10F, T74P I15V, L19I, K20IMT, M36I, R41K, K43R, Q61H, I62V, L63T, I64V, H69K, L89M, I93L  
>F36402| codons 1-99
PQITLWQRPFVTIKVGGQITEALLDTGADDTVLEEINLPGKWRPKIIGGIGGFIKVRQYD
HVTVEICGKKAIGPVLVGPTPVNVIGRNMMTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K70KR, M184V       V35T, T39E, S48T, W88C, K104KR, K122E, D123G, I135MT, E138A, Q174R, D177E, V179I, T200A, Q207E, F214L, V245Q, D250E, A272P, K277R, T286A, E291D, V292I, I293V, K311KR, D324E  
>F36402| codons 1-333
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEGKITKIGPENPYNTPV
FAIKKKDSTRWRKLVDFRELNKRTQDFCEVQLGIPHPAGLKKKRSVTVLDVGDAYFSVPL
DEGFRKYTAFTIPSTNNATPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKRNPEIII
YQYVDDLYVGSDLEIGQHRAKIEELREHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKESWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDIVPLTEEAE
LELAENREILREPVHGVYYDPSKELIAEIQKQG

References
Author Title Citation
Weber, J Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005