Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| F58125 | F58125 | U.K. | 2003 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 35 |
| 2 | D4T+ AZT+ 3TC | 104 |
| 3 | Unknown | 104 |
| 4 | NVP+ DDI+ D4T | 52 |
| 5 | TDF+ NVP+ DDI+ ABC | 77 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K65R | V106M, Y181C | K22KN, T27TP, V35T, E36A, T39E, S48T, K122E, D123G, T139I, S162C, K166R, K173A, D177E, T200A, Q207E, V245Q, E248EK, E291D, V292I, I293V, S322SA | K13KN |
| >F58125| codons 1-333 PISPIETVPVKLNPGMDGPKVNQWPLPEEKIKALTAICEEMEKEGKITKIGPENPYNTPV FAIKRKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSMTVLDVGDAYFSVPL DEGFRKYTAFTIPSINNEIPGIRYQYNVLPQGWKGSPAIFQCSMTRILEPFRAQNPEIVI CQYMDDLYVGSDLEIGQHRAKIEELREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPKKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPAKDLIAEIQKQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19I, K20R, T31TP, E35D, M36I, R41K, K43KN, R57RS, H69K, L89M, I93L | L23LF |
| >F58125| codons 1-99 PQITLWQRPLVSIKVGGQIREAFLDTGADDPVLEDINLPGKWNPKMIGGIGGFIKVSQYD QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Weber, J | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |