Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| F66883 | F66883 | U.K. | 2003 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ AZT | 95 |
| 2 | D4T+ NVP+ DDI | 167 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K101KE, Y181C, G190A | D17DG, V35T, E36A, T39E, S48T, D123E, I135V, K173T, D177E, T200A, Q207E, L228R, V245Q, A272P, K277R, E291D, I293V, P321S |
| >F66883| codons 1-334 PISPIETVPVKLKPGMGGPKVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLEKKKSVTVLDVGDAYFSVPL DKEFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTQNPEIVI CQYMDDLYVASDLEIGQHRAKIEELREHLLRWGFTTPDKKHQKEPPFRWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTDVVPLTEEAE LELAENREILKEPVHGVYYDSSKDLIAEIQKQGQ |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, Q18QP, L19IT, L24LF, M36I, R41K, L63V, H69K, L89LM, I93L | R8RP |
| >F66883| codons 1-99 PQITLWQPPLVSIKVGGPTKEALFDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QIVIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Weber, J | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |