<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
939949 939949 U.K. 2003 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 EFV+ DDI+ D4T 60
2 ABC+ 3TC+ LPV 22

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19M, E35D, M36I, H69K, L89M, I93L  
>939949| codons 1-99
PQITLWQRPLVSIKVGGQMKEALLDTGADDTVLEDINLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
    K103N, V106M   V35T, E36A, T39E, S48T, D123S, T139A, S162C, Q174N, T200A, Q207E, R211K, F214L, L228LR, V245Q, A272S, K277R, T286A, E291D, V292I, I293V P157PL
>939949| codons 1-333
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSMTVLDVGDAYFSVPL
DKSFRKYTAFTIPSINNEAPGIRYQYNVLPQGWKGSLAIFQCSMTKILEPFRKNNPDIVI
YQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGLTTPDKKHQKEPPFRWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYSGIKVRQLCKLLRGAKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQG

References
Author Title Citation
Weber, J Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005