Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| F30020 | F30020-2 | U.K. | 2003 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+DDI+NVP | 79 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K65R | Y181C | E6D, E28A, V35T, V60I, V118I, K122E, D123N, I135T, K173S, Q174K, D177E, I178L, V179I, T200A, E204ED, R211K, F214L, V245Q, D250E, A272P, T286A, E291D, I293V, P294A, E312D, V317A | I159IL, Q207*E |
| >F30020-2| codons 1-334 PISPIDTVPVKLKPGMDGPKVKQWPLTAEKIKALTEICTEMEKEGKISKIGPENPYNTPI FAIKRKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL DENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPALFQSSMTKILEPFRSKNPELII CQYMDDLYVGSDLEIGQHRAKIEDLREHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDVVALTEEAE LELAENREILKDPVHGAYYDPSKDLIAEIQKQGQ |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K14R, I15V, E35D, M36I, R41K, R57K, H69K, L89M |
| >F30020-2| codons 1-99 PQITLWQRPLVTVRVGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Weber, J | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |