<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
RC-034-040-486 040-4861 Peru 2000 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 ATV+AZT+3TC NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I50L   L10V, K14R, M36I, A71AV, L89M  
>040-4861| codons 1-99
PQITLWQRPVVTIRIGGQLKEALLDTGADDTVLEEINLPGRWKPKMIGGLGGFIKVRQYD
QILIEICGHKVIGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005
Colonno, RJ Identification of I50L as the signature atazanavir (ATV)-resistance mutation in treatment-naive HIV-1-infected patients receiving ATV-containing regimens. J Infect Dis, 2004