Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| SR_Pat33 | SR149695 | U.S. | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|RTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, I84V, L90M | L10F, V11I | T4P, I13V, K20I, E35D, M36I, N37H, R41K, F53FY, D60DE, I62V, L63P, K70N, A71V, P79A, T91S, Q92K, N98I |
| >SR149695| codons 1-99 PQIPLWQRPFITVKIGGQLIEALLDTGADDTVLEDIHLPGKWKPKIIGGIGGYVKVRQYE QVPIEICGHNVIGTVLVGATPVNVIGRNLMSKIGCTLIF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | K122E, I142V, E169D, T200A, Q207E, V245K, I293IV, E297V, D324E, Q334D |
| >SR149695| codons 1-335 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILDPFRKQNPDIVI YQYVDDLYVGSDLEIGQHRAKIEELREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIKLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKALTEVVPLTVEAE LELAENREILKEPVHGVYYDPSKELIAEIQKQGDG |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |
| Rhee, SY | HIV-1 protease mutations and protease inhibitor cross resistance. | AAC, 2010 |