Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| SR_Pat26 | SR196077 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|RTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, I84V, L90M | L10F, V11I | T4P, I13V, K20I, A22AV, E35D, M36I, N37H, R41K, D60E, I62V, L63P, A71V, I72IL, P79AD, T91S, Q92K |
| >SR196077| codons 1-99 PQIPLWQRPFITVKIGGQLIEVLLDTGADDTVLEDIHLPGKWKPKIIGGIGGFVKVRQYE QVPIEICGHKVLGTVLVGATPVNVIGRNLMSKIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | K103NS | K122E, I142V, E169D, T200A, Q207E, V245K, K277X, I293V, E297V, A304AE, D324E, Q330P, Q334D |
| >SR196077| codons 1-335 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILDPFRKQNPDIVI YQYVDDLYVGSDLEIGQHRAKIEELREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIKLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVXQLCKLLRGTKALTEVVPLTVEAE LELEENREILKEPVHGVYYDPSKELIAEIPKQGDG |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |
| Rhee, SY | Genotypic predictors of human immunodeficiency virus type 1 drug resistance. | PNAS, 2006 |