Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA18428 | CA43003 | U.S. | 2004 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+IDV | 441 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V32I, M46MI, I47V | I3IN, L10I, I62V, L63A, A71T, V77I, I85V, Q92K, I93L |
| >CA43003| codons 1-99 PQNTLWQRPIVTIKIGGQLKEALLDTGADDTILEEMNLPGRWKPKIVGGIGGFIKVRQYD QVAIEICGHKTIGTVLIGPTPVNIVGRNLLTKLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, M184V | E28K, K32E, V35I, F77FS, R83K, K101Q, K122E, I135V, V245K, K281R, I293V, E297EK |
| >CA43004| codons 1-367 PISPIETVPVKLKPGMDGPKVKQWPLTKEKIEALIEICTEMEKEGKISKIGPENPYNTPV FAIKKKNSTRWRKLVDSRELNKKTQDFWEVQLGIPHPAGLQKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYVDDLYVGSDLEIGQHRTKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIKLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCRLLRGTKALTEVVPLTKEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGA HTNDVKQ |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |