Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA18384 | CA42916 | U.S. | 2004 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | Unknown | 52 |
| 2 | 3TC+NVP+TDF | 52 |
| 3 | 3TC+EFV+TDF | 18 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, K65KR, M184V, L210W, T215DY | A62AV | V106A, G190A | F227FL | E6EK, K20R, V35I, K122E, I135T, S162A, G196E, T200A, I202V, E203EQ, Q207E, R211K, K277R, I293V, T296S, E297K | S68SDGN |
| >CA42916| codons 1-300 PISPIKTVPVKLKPGMDGPRVKQWPLTEEKIKALIEICTELEKEGKISKIGPENPYNTPV FVIKRKDNTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSATVLDVGDAYFSVPL DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRKQNPDIVI YQYVDDLYVASDLEIEQHRAKVQELREHLWKWGFYTPDKKHQKEPPLLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLLRGTKALTEVVPLSKEAE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82A | L24I | L10I, T12D, L19I, M36I, N37S, R41K, I62V, L63P, A71V |
| >CA42915| codons 1-99 PQITLWQRPIVDIKIGGQIKEALIDTGADDTVLEEISLPGKWKPKMIGGIGGFVKVRQYD QVPIEICGHKVIGTVLVGPTPANIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |