Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA18383 | CA42914 | U.S. | 2004 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+DDI+IDV | 375 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L74V, L210W, T215Y | K101E | K32N, V35T, K49KR, S68G, V118I, K122E, D123E, I135R, D177E, I178L, E203DN, Q207E, R211K, K223KQ, V245K, E297T |
| >CA42914| codons 1-300 PISPIETVPVKLKPGMDGPKVKQWPLTEEKINALTEICTELEKEGKISRIGPENPYNTPV FAIKKKDGTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLEKKKSVTVLDVGDAYFSIPL DEEFRKYTAFTIPSRNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPELVI YQYMDDLYVGSDLEIGQHRTKINELREHLWKWGFYTPDKKHQQEPPFLWMGYELHPDKWT VQPIKLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKALTEVIPLTTEAE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90M | Q58E | L10I, E35G, M36I, I62V, L63A, I93L, C95F |
| >CA42913| codons 1-99 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEGINLPGRWKPKMIGGIGGFIKVREYD QVAIEICGHKAIGTVLVGPTPVNIIGRNLMTQLGFTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |