Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA16329 | CA42771 | U.S. | 2004 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+IDV | 169 |
| 2 | 3TC+ABC+AZT | 52 |
| 3 | 3TC+ABC+AZT+IDV+RTV | 193 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, L76V, L90M | L10V, Q18H, L19V, K20T, E21Q, N37D, K55R, R57K, D60E, I62V, L63P, C67F, H69Q, A71V, I72M, V77I, I93L | C95I |
| >CA42771| codons 1-99 PQITLWQRPVVTIKIGGHVTQALLDTGADDTVLEEMDLPGRWKPKIIGGIGGFIRVKQYE QVPIEIFGQKVMGTVVIGPTPVNIIGRNLMTQLGITLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, M184V, L210W, T215Y | K43KDEN, E44D, V111I, V118VI, D123E, S162F, I178L, V189VI, G196E, T200A, E203D, H208F, R211KN, A272P, K277R, A288AT, I293V, E297A, G333E |
| >CA42772| codons 1-344 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELENDGKISKIGPENPYNTPV FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDIGDAYFSIPL DKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQFSMTKILEPFRKQNPDLVI YQYVDDLYIGSDLEIEQHRAKIDELRQFLWNWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKTLTEVVPLTAEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQEQGQWTYQIYQE |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |