Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA4743 | CA42712 | U.S. | 2004 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC | 78 |
| 2 | 3TC+D4T+IDV | 126 |
| 3 | 3TC+D4T+IDV+RTV | 26 |
| 4 | 3TC+D4T+NFV | 180 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, T69D, K70R, M184MV, T215F | D67G | T7TA, T39TA, S68G, I135T, S162Y, Q174H, Q207E, L228Q, V245VM |
| >CA42712| codons 1-251 PISPIEAVPVKLKPGMDGPKVKQWPLTEEKIKALVEICAELEKEGKISKIGPENPYNTPV FAIKKKGGDRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQYSMTKILEPFRKHNPDIVI YQYVDDLYVGSDLEIGQHRTKIEELREHLLRWGFFTPDKKHQKEPPFQWMGYELHPDKWT VQPIMLPEKDS |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V32I, M46I, V82A, L90M | L10F, K43T | L19I, M36MI, N37NS, L38LF, K55R, L63P, H69Q, A71V, I72IV |
| >CA42711| codons 1-99 PQITLWQRPFVTIKIGGQIKEALLDTGADDTILEEISFPGRWTPKIIGGIGGFIRVRQYD QIPIEICGQKVVGTVLVGPTPANIIGRNLMTQIGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |