Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA6602 | CA42706 | U.S. | 2004 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | Unknown | 52 |
| 2 | ABC+EFV | 65 |
| 3 | APV+LPV+TDF | 141 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| T215Y | A62V | K103N | W88WS, K122E, I135IT, E138Q, S162C, E169D, I178L, T200A, R211K, L228R, I244IV, D250E, I257L, K277R, T286A, A288S, I293V, T296S, E297R, L301I, I329L, G333E |
| >CA42706| codons 2-335 ISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVF VIKKKDSTKWRKLVDFRELNKRTQDFSEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPLD EDFRKYTAFTIPSTNNQTPGIRYQYNVLPQGWKGSPAIFQCSMTKILDPFRKQNPDLVIY QYMDDLYVGSDLEIGQHRAKIEELRQHLLKWGFYTPDKKHQKEPPFRWMGYELHPDKWTV QPVVLPEKESWTVNDLQKLVGKLNWASQIYAGIKVRQLCKLLRGAKSLTEVVPLSREAEI ELAENREILKEPVHGVYYDPSKDLIAELQKQEQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, V82F, L90M | L33F, K43T, G73A | L10I, K20R, E35D, M36I, R57K, Q61E, I62V, L63P, I64V, I72IT, I93L |
| >CA42705| codons 1-99 PQITLWQRPIVTIKIGGQLREALLDTGADDTVFEDINLPGRWTPKIIGGIGGFVKVKQYD EVPVEICGHKATATVLVGPTPFNIIGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |