Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA1288 | CA42699 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T | 4 |
| 2 | 3TC+AZT | 26 |
| 3 | 3TC+AZT+IDV | 43 |
| 4 | AZT+DDI+IDV+NVP | 17 |
| 5 | 3TC+D4T+RTV+SQV | 82 |
| 6 | 3TC+D4T+EFV+SQV | 24 |
| 7 | Unknown | 194 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| N37A, R41K, I62IV, L63A, A71AV, V77I, I93L, L97LI |
| >CA42699| codons 1-99 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMALPGKWKPKMIGGIGGFIKVRQYD QVAIEICGHKVIGTVLIGPTPVNIIGRNLLTQLGCTINF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K122E, D123DN, I135IV, Q207QE, R211K, F214L, V245T, K277R, T286A, V292I, I293V, E297A |
| >CA42700| codons 1-301 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYMDDLYVGSDLEIGQHRTKIEELREHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPITLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLLRGAKALTEIVPLTAEAE L |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |