Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA4797 | CA42691 | U.S. | 2004 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 61 |
| 2 | None | 57 |
| 3 | 3TC+IDV | 22 |
| 4 | 3TC+AZT+IDV | 270 |
| 5 | D4T+NVP+RTV+SQV | 59 |
| 6 | 3TC+LPV+TDF | 62 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, V82F, L90M | L10I, L19Q, K20I, M36MI, I64V, A71V, V77I, I85V, I93L |
| >CA42691| codons 1-99 PQITLWQRPIVTIKIGGQQIEALLDTGADDTVLEEINLPGRWKPKIIGGIGGFVKVRQYD QILVEICGHKVIGTVLIGPTPFNIVGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, M184V, L210W, T215Y | K43Q, E44D, K122E, D123N, Q207A, R211K, V245M, E248D, D250E, R284K, I293V | T286R |
| >CA42692| codons 1-300 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEQDGKISKIGPENPYNTPV FAIKKKNSDKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYVDDLYVGSDLEIGQHRTKIEELRAHLWKWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIMLPDKESWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLKGRKALTEVVPLTEEAE |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |