Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA1824 | CA42679 | U.S. | 2004 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T | 109 |
| 2 | 3TC+D4T+IDV | 152 |
| 3 | 3TC+D4T+DDI+RTV+SQV | 150 |
| 4 | D4T+EFV+LPV+TDF | 24 |
| 5 | 3TC+D4T+DLV+LPV+TDF | 90 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I84V, L90M | G73T | L10I, K20I, I62V, L63P, C67F, V77I |
| >CA42679| codons 1-99 PQITLWQRPIVTIKIGGQLIEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIKVRQYD QVPIEIFGHKAITTVLIGPTPVNVIGRNLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, M184V, L210W, T215Y | K22N, V35T, T39A, K43E, S68G, D123E, K166Q, E169D, D177E, T200A, L228H, V245E, A272P, I293V |
| >CA42680| codons 1-301 PISPIETVPVKLKPGMDGPKVNQWPLTEEKIKALTEICAELEEEGKISKIGPENPYNTPV FAIKKKDGTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTQILDPFRKQNPEIVI YQYVDDLYVGSDLEIGQHRAKIEELRQHLWRWGFYTPDKKHQKEPPFHWMGYELHPDKWT VQPIELPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVVPLTEEAE L |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |