Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA9710 | CA42665 | U.S. | 2004 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | Unknown | 52 |
| 2 | 3TC+D4T+EFV+LPV | 9 |
| 3 | None | 35 |
| 4 | 3TC+APV+D4T+RTV | 9 |
| 5 | 3TC+ABC+AZT | 30 |
| 6 | None | 22 |
| 7 | 3TC+D4T+LPV | 70 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90M | G73GS | L10I, T12E, K20I, E35D, M36MI, I62V, L63P, K70R, A71V, V77I, I93IL |
| >CA42665| codons 1-99 PQITLWQRPIVEIKIGGQLIEALLDTGADDTVLEDINLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHRVISTVLIGPTPVNIIGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184MV | T215TILP | G190A | V35E, T39A, K101S, K122KE, I135K, V179I, R211K, I244IV, V245VAMT, A272P, K281KR, T286A |
| >CA42666| codons 1-302 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALEEICAEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLSKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSKNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIII YQYVDDLYVASDLEIGQHRTKIEELRQHLLKWGFPTPDKKHQKEPPFLWMGYELHPDKWT VQPVTLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLLRGAKALTEVIPLTEEAE LE |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |