Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA5719 | CA42644 | U.S. | 2004 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+NFV | 332 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, M184V, T215F | K102Q, D123E, I135T, E138A, T139M, I142V, S162C, D177E, V179I, T200I, V245MT, T286A, P294PQ |
| >CA42644| codons 1-300 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKQKKSVTVLDVGDAYFSVPL DKEFRKYTAFTIPSTNNAMPGVRYQYNVLPQGWKGSPAIFQCSMTKILEPFRKQNPEIII YQYVDDLYVGSDLEIGQHRIKIEELRQHLLRWGFFTPDKKHQKEPPFLWMGYELHPDKWT VQPITLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTEVIQLTEEAE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, L90M | T12S, L19IT, K20I, D60E, I62V, L63P, I64V, H69Q, T74A, V77I |
| >CA42643| codons 1-99 PQITLWQRPLVSIKIGGQTIEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIKVRQYE QVPVEICGQKAIGAVLIGPTPVNIIGRNLMTQIGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |