Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA1502 | CA42635 | U.S. | 2004 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+DDI+RTV | 35 |
| 2 | 3TC+D4T+NFV | 187 |
| 3 | Unknown | 114 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I54V, L76V, V82A, L90M | L10I, I15V, L19I, K20R, M36I, R41K, L63P, A71V, I93L |
| >CA42635| codons 1-99 PQITLWQRPIVTIKVGGQIREALLDTGADDTVLEEINLPGKWKPKLIGGIGGFVKVRQYD QIPIEICGHKVIGTVVVGPTPANIIGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, M184V, T215CFGV | K219Q | K103N | V108I | K20R, V35M, V60VI, K64R, K101S, K122P, I135T, D177E, I178IL, I202IV, Q207QR, K223KT, A272P, K277R, Q278QH, T286A, I293V | W24WR, L282LF, L283LF |
| >CA42636| codons 1-301 PISPIETVPVKLKPGMDGPRVKQRPLTEEKIKALMEICTEMEKEGKISKIGPENPYNTPI FAIRKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLSKNKSVTILDVGDAYFSVPL DPDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPELVI YQYVDDLYVGSDLEIGQHRTKVEELRRHLLRWGFVTPDQKHQTEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRHLCKFFRGAKALTEVVPLTEEAE L |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |