<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
IL720 IL720 Israel 2003 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 IDV+ NVP+ DDI+ D4T+ AZT+ 3TC 341

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    Q7R, I15V, L19I, M36I, R41K, H69K, L89M, I93L  
>IL720| codons 7-99
RRPLVTIKVGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYDQILIEI
CGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70R   K103KT, V106M, G190A   T39E, S48T, K122E, D123DGNS, I142T, A158S, K166R, K173A, D177E, G196R, T200A, I202V, E203EK, Q207E, D237DN, V245Q E53EA
>IL720| codons 38-247
CEEMEKEGKITKIGPANPYNTPVFAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHP
AGLKKTKSMTVLDVGDAYFSVPLDESFRKYTAFTIPSINNETPGTRYQYNVLPQGWKGSP
SIFQSSMTRILEPFRAQNPEIVIYQYMDDLYVASDLEIRQHRAKVKELREHLLRWGFTTP
DKKHQKEPPFLWMGYELHPNKWTVQPIQLP

References
Author Title Citation
Grossman, Z Mutation D30N is not preferentially selected by human immunodeficiency virus type 1 subtype C in the development of resistance to nelfinavir. AAC, 2004