<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
IL708 IL708 Israel 2003 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 D4T+ 3TC+ NFV 44

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I84C   I15V, K20R, M36I, R41K, L63T, H69K, I72T, I93L  
>IL708| codons 4-99
TLWQRPLVTIKVGGQLREALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYDQIT
IEICGKKATGTVLVGPTPVNCIGRNLLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V       T39D, K43R, K102KR, K104R, K166KR, K173AT, D177E, T200A, Q207E, V245Q  
>IL708| codons 38-246
CDEMEREGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP
AGLKRKRSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP
AIFQSSMTRILEPFRTQNPEIVIYQYVDDLYVGSDLEIGQHRAKIEELREHLLRWGFTTP
DKKHQKEPPFLWMGYELHPDKWTVQPIQL

References
Author Title Citation
Grossman, Z Mutation D30N is not preferentially selected by human immunodeficiency virus type 1 subtype C in the development of resistance to nelfinavir. AAC, 2004