<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
IL642 IL642 Israel 2003 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 NVP+ DDI+ D4T+ AZT+ 3TC+ NFV 229

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
  I47IM I15V, M36I, R41K, H69K, L89M, I93L  
>IL642| codons 4-99
TLWQRPLVTIKVGGQLKEALLDTGADDTVLEEINLPGKWKPKMMGGIGGFIKVRQYDQIL
IEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
    Y188L V179D T39E, K122E, D123S, S162A, K173T, D177E, T200A, Q207E, R211K, V245Q  
>IL642| codons 38-247
CEEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP
AGLKKKKSVTVLDVGDAYFSVPLDESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP
AIFQASMTKILEPFRTQNPEIDIYQYMDDLLVGSDLEIGQHRAKIEELREHLLKWGFTTP
DKKHQKEPPFLWMGYELHPDKWTVQPIQLP

References
Author Title Citation
Grossman, Z Mutation D30N is not preferentially selected by human immunodeficiency virus type 1 subtype C in the development of resistance to nelfinavir. AAC, 2004