Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| IL574 | IL574 | Israel | 2003 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ 3TC | 1 |
| 2 | NFV+ 3TC+ AZT | 56 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N | Q7H, I15V, L19I, K20T, M36I, N37S, R41K, L63S, H69K, I93L | R8A |
| >IL574| codons 4-99 TLWHAPLVTIKVGGQITEALLDTGADNTVLEEISLPGKWKPKMIGGIGGFIKVRQYDQIS IEICGKKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K70KR, M184V | T39E, S48T, K122E, D123N, I135IV, K173A, D177E, G196K, T200A, Q207E, R211K, V245Q |
| >IL574| codons 38-247 CEEMEKEGKITKIGPENPYNTPVFAIKKKDSTRWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKKKSVTVLDVGDAYFSVPLDENFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRAQNPEIVIYQYVDDLYVGSDLEIKQHRAKIEELREHLLKWGFTTP DKKHQKEPPFLWMGYELHPDKWTVQPIQLP |
References
| Author | Title | Citation |
| Grossman, Z | Mutation D30N is not preferentially selected by human immunodeficiency virus type 1 subtype C in the development of resistance to nelfinavir. | AAC, 2004 |