<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
IL433 IL433b Israel 2003 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 DDC+ AZT+ IDV 174

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, L210W, T215Y       T39E, V118VI, K122E, D123E, A158S, K173A, Q174K, D177E, I178M, T200A, Q207E, L228LR, V245Q  
>IL433b| codons 38-247
CEELEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP
AGLKKKKSVTVLDVGDAYFSIPLDEEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP
SIFQSSMTKILEPFRAKNPEMVIYQYMDDLYVGSDLEIGQHRAKIEELREHLWRWGFYTP
DKKHQKEPPFRWMGYELHPDKWTVQPIQLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, V82A, L90LM L10F, Q58QE I15V, K20R, M36I, L63PT, H69K, L89M, I93L  
>IL433b| codons 4-99
TLWQRPFVTIKVGGQLREALLDTGADDTVLEEINLPGRWKPKLIGGIGGFIKVREYDQIT
IEICGKKAIGTVLVGPTPANIIGRNMMTQLGCTLNF

References
Author Title Citation
Grossman, Z Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005
Non-B Workgroup Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005