Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| IL384 | IL384a | Israel | 2000 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ DDC | 17 |
| 2 | AZT+ DDC+ IDV | 25 |
| 3 | AZT+ IDV | 39 |
| 4 | 3TC+ D4T+ SQV+ RTV | 26 |
| 5 | 3TC+ D4T+ SQV | 8 |
| 6 | None | 4 |
| 7 | NFV+ 3TC+ D4T | 39 |
| 8 | D4T+ NFV+ SQV+ RTV+ 3TC | 13 |
| 9 | SQV+ RTV+ 3TC+ D4T | 4 |
| 10 | DDI+ ABC+ NVP+ D4T | 14 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, V82A, L90M | T74P | W6WL, L10V, I15V, K20KI, M36I, N37D, R41K, L63P, H69K, A71V, L89M, I93L |
| >IL384a| codons 4-99 TLLQRPVVTIKVGGQLIEALLDTGADDTVLEEIDLPGKWKPKIIGGIGGFVKVRQYDQIP IEICGKKVIGPVLVGPTPANIIGRNMMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, T215Y | A62V | Y181YC, Y188FL | T69S, K104R, K122E, K173I, Q174R, D177E, I178L, T200A, Q207E, V245Q |
| >IL384a| codons 40-247 ELEKEGKISKIGPENPYNTPVFVIKKKDSSKWRKLVDFRELNKRTQDFWEVQLGIPHPAG LKKKRSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAI FQSSMTKILEPFRIRNPELVICQYMDDLLVGSDLEIGQHRAKIEELREHLLRWGFYTPDK KHQKEPPFLWMGYELHPDKWTVQPIQLP |
References
| Author | Title | Citation |
| Grossman, Z | Mutation D30N is not preferentially selected by human immunodeficiency virus type 1 subtype C in the development of resistance to nelfinavir. | AAC, 2004 |