<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
IL370 IL370 Israel 2002 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 NFV+ 3TC+ AZT 55

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
D30DN, N88NDGS L10F T12S, L19V, K20KM, M36I, R41K, L63LP, H69K, T74S, L89IM, I93L  
>IL370| codons 4-99
TLWQRPFVSIKIGGQVMEALLDTGADNTVLEEINLPGKWKPKMIGGIGGFIKVRQYDQIP
IEICGKKAIGSVLVGPTPVNIIGRSMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V       T39D, A98S, K122E, D123S, I135L, K173A, Q174K, D177E, T200A, Q207E, V245Q  
>IL370| codons 38-247
CDEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP
SGLKKKKSVTVLDVGDAYFSVPLDESFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSP
AIFQSSMTKILEPFRAKNPEIVIYQYVDDLYVGSDLEIGQHRAKIEELREHLLRWGFTTP
DKKHQKEPPFLWMGYELHPDKWTVQPIQLP

References
Author Title Citation
Grossman, Z Mutation D30N is not preferentially selected by human immunodeficiency virus type 1 subtype C in the development of resistance to nelfinavir. AAC, 2004