<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
IL351 IL351 Israel 2002 HIV1 A Plasma None

Treatment History
Order Regimen Weeks
1 NFV+ 3TC+ AZT 226

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V       T39K, D121DH, K122E, D123S, A158S, K173LS, Q174K, D177E, T200TA, Q207A, R211S, F214FL, E233EG N137NI
>IL351| codons 38-244
CKEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP
AGLKKKKSVTVLDVGDAYFSVPLHESFRKYTAFTIPSINIETPGIRYQYNVLPQGWKGSP
SIFQSSMTKILEPFRSKNPEIVIYQYVDDLYVGSDLEIGQHRAKIEELRAHLLSWGLTTP
DKKHQKEPPFLWMGYGLHPDKWTVQPI

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I Q58QE I13V, K14KR, K20KR, E35ED, M36I, N37ND, R41K, H69K, L89I, I93L  
>IL351| codons 4-99
TLWQRPLVTVRIGGQLREALLDTGADDTVLEDIDLPGKWKPKIIGGIGGFIKVREYDQIL
IEICGKKAIGTVLVGPTPVNIIGRNILTQLGCTLNF

References
Author Title Citation
Grossman, Z Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005
Non-B Workgroup Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005