Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| IL280 | IL280b | Israel | 2000 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 52 |
| 2 | DDC+DDI+NVP | 104 |
| 3 | AZT+DDC+SQV | 104 |
| 4 | ABC+D4T+IDV | 97 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46MI, I84V, L90M | T12S, I15V, Q18L, M36I, R41RK, L63P, H69KR, A71V, T74S, L89M, I93L | D29DG, R87RT |
| >IL280b| codons 4-99 TLWQRPLVSIKVGGLLKEALLDTGAGDTVLEEINLPGKWKPKIIGGIGGFIKVRQYDQIP IEICGRKVIGSVLVGPTPVNVIGTNMMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, M184MIV, T215Y | K219KE | V106M, Y188YC | T39E, D86DN, A98S, K101KR, K122E, D123S, R125RG, S134SG, A158S, S162A, K173A, D177E, I178L, T200A, Q207E, V245Q |
| >IL280b| codons 38-247 CEEMEKEGKISKIGPENPYNTPVFAIKKKNSTRWRKLVDFRELNKRTQNFWEVQLGIPHP SGLRKKKSMTVLDVGDAYFSVPLDESFGKYTAFTIPGINNETPGIRYQYNVLPQGWKGSP SIFQASMTKILEPFRAQNPELVIYQYVDDLCVGSDLEIGQHRAKIEELREHLLRWGFYTP DEKHQKEPPFLWMGYELHPDKWTVQPIQLP |
References
| Author | Title | Citation |
| Grossman, Z | Mutation D30N is not preferentially selected by human immunodeficiency virus type 1 subtype C in the development of resistance to nelfinavir. | AAC, 2004 |