Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| IL267 | IL267 | Israel | 2001 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 17 |
| 2 | DDC+ AZT | 117 |
| 3 | AZT+ IDV+ 3TC | 12 |
| 4 | 3TC+ AZT+ RTV | 8 |
| 5 | AZT+ SQV+ 3TC | 95 |
| 6 | NFV+ 3TC+ AZT | 114 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | A98G | T39E, S48T, K49R, K122E, D123S, I135IMT, A158AS, S162SN, K173AT, D177DE, T200A, Q207E, V245Q |
| >IL267| codons 38-247 CEEMEKEGKITRIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP GGLKKKKSVTVLDVGDAYFSVPLDESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP SIFQNSMTKILEPFRTQNPEIVIYQYVDDLYVGSDLEIGQHRAKIEELREHLLRWGFTTP DKKHQKEPPFLWMGYELHPDKWTVQPIQLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90M | I13IV, K14R, I15V, G16GE, K20T, E35D, M36I, R41K, H69K, A71AV, T74S, L89I, I93L |
| >IL267| codons 4-99 TLWQRPLVTVRVEGQLTEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYDQIL IEICGKKVIGSVLVGPTPVNIIGRNIMTQLGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |
| Grossman, Z | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |