Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| IL266 | IL266 | Israel | 2001 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | RTV+ SQV+ AZT | 65 |
| 2 | RTV+ SQV+ 3TC+ AZT | 39 |
| 3 | IDV | 13 |
| 4 | IDV+ RTV | 35 |
| 5 | NFV | 28 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54IL, I84V, L90M | T74TP | L10I, I15V, K20KI, E35EG, M36I, R41RK, L63P, H69K, A71V, L89M, Q92QR, I93L | R8RG |
| >IL266| codons 4-99 TLWQGPIVTIKVGGQLIEALLDTGADDTVLEGINLPGKWKPKMIGGIGGFLKVRQYDQIP IEICGKKVIGPVLVGPTPVNVIGRNMMTRLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V, T215Y | A62V | T39D, S48T, K122E, A158S, K173T, Q174K, T200A, Q207D, R211K, V245Q |
| >IL266| codons 38-247 CDEMEKEGKITKIGPENPYNTPVFVIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP SIFQSSMTKILEPFRTKNPDIVIYQYVDDLYVGSDLEIGQHRAKIEELRDHLLKWGFYTP DKKHQKEPPFLWMGYELHPDKWTVQPIQLP |
References
| Author | Title | Citation |
| Grossman, Z | Mutation D30N is not preferentially selected by human immunodeficiency virus type 1 subtype C in the development of resistance to nelfinavir. | AAC, 2004 |