Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| IL265 | IL265 | Israel | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ AZT | 41 |
| 2 | 3TC+ AZT+ IDV | 173 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, L76V | L89LV | I13V, I15V, K20T, R41K, K55R, I62V, L63P, I64IV, I93L |
| >IL265| codons 4-99 TLWQRPLVTVKVGGQLTEALLDTGADDTVLEEMNLPGKWKPKIIGGIGGFIRVRQYDQVP VEICGHKAIGTVVVGPTPVNIIGRNVLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, M184V | D123E, S134SG, I135T, S162C, G196GR, T200A, Q207E, R211K, K223KR |
| >IL265| codons 38-247 CTEMEKEGKISKIGPENPYNTPVFAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKKKSVTVLDVGDAYFSVPLDKEFRKYTAFTIPGTNNETPGIRYQYNVLPQGWKGSP AIFQCSMTKILEPFRKQNPDIVIYQYVDDLYVGSDLEIRQHRAKIEELREHLLKWGFTTP DKKHQREPPFLWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |
| Grossman, Z | Mutation D30N is not preferentially selected by human immunodeficiency virus type 1 subtype C in the development of resistance to nelfinavir. | AAC, 2004 |